Improving Machine Learning Classification Predictions through SHAP and Features Analysis Interpretation 2025 Spoke 5 Advanced technologies and experimental models L. Bernal, G. Rastelli, L. Pinzi.
Organ-on-chip immunostaining method for three-dimensional identification and study of immune cells responding to drug-treated tumor cells 2025 Spoke 7 Oncology and innovative therapies Advanced technologies and experimental models Francesco Noto, Adele De Ninno, Mario Falchi, Luca Businaro, Giovanna Schiavoni, Fabrizio Mattei
Harnessing Self-Sensitized Scintillation by Supramolecular Engineering of CsPbBr3 Nanocrystals in Dense Mesoporous Template Nanospheres 2026 Spoke 6 Advanced technologies and experimental models Zhou X, Zaffalon ML, Mazzola E, Fratelli A, Carulli F, Wang C, He M, Bruni F, Chakraborty S, Poletti L, Rossi F, Gironi L, Meinardi F, Li L, Brovelli S.
Precondensed Plasmid DNA Enhances CAR‑T Cell Generation via Lipid Nanoparticles 2025 Spoke 5 Advanced technologies and experimental models Pirrottina, A.; Renzi, S.; Digiacomo, L.; Giulimondi, F.; De Lorenzi, V.; Ghignoli, S.; Pesce, L.; Cardarelli, F.; Mura, F.; Parisi, G.; Buccini, L.; Cassone, C.; Zingoni, A.; Pozzi, D.; Caracciolo, G.
A gene-expression signature defines a subtype of Stomach Adenocarcinomas with low levels of Claudins and a high ratio of NF-YA long/NF-YA short splicing variants 2026 Spoke 5 Oncology and innovative therapies Alberto Gallo, Mirko Ronzio, Maria Barbara Campbell, Sofia Polettini, Enrico Garattini, Roberto Mantovani, Diletta Dolfini.
From Optoelectronics to Radiation Detection: Light Yield Challenges in Perovskite Scintillators 2025 Spoke 6 Advanced diagnostics Zaffalon ML, Gironi L, Nikl M, Brovelli S.
A calix[4]arene-based supramolecular nanoassembly targeting cancer cells and triggering the release of nitric oxide with green light 2025 Spoke 6 Advanced technologies and experimental models Parisi C, Ferreri L, Martins TJ, Laneri F, Sollima S, Azzolina A, Cusimano A, D’Antona N, Consoli GML, Sortino S.
Bio-based hydrogel patches made of κ-carrageenan enriched with degalactosylated xyloglucan for wound dressing applications 2025 Spoke 6 Advanced technologies and experimental models Muscolino E, Dispenza C.
Fecal microbiota transplantation for decolonization from multidrug-resistant bacteria in pediatric allogeneic hematopoietic stem cell transplantation recipients: a retrospective real-world data study 2025 Spoke 5 Advanced technologies and experimental models Masetti R, Barbara G, Muratore E, Marasco G, Cremon C, Marangoni A, Brigidi P, Putignani L, Angelino G, Quagliarella F, Galaverna F, Leardini D, Lazzarotto T, Gabelli M, Savarino E, Zecca M, Faraci M, Prete A, Biffi A, Locatelli F, Merli P.
Validation of Hemoglobin and Hematocrit Measurements from a Dialysis Machine Sensor Compared to Laboratory Analysis 2025 Spoke 6 Advanced diagnostics Morisi N, Ferrarini M, Veronesi L, Manzini G, Giovanella S, Alfano G, Stipo L, Olmeda F, Ligabue G, Virzì GM, Di Pinto V, Rovati L, Donati G.
Hematopoietic stem cell transplantation disrupts age-related gut microbiota signatures in pediatric and adult recipients 2025 Spoke 5 Advanced technologies and experimental models Leardini D, Roberto M, Roggiani S, Muratore E, Fabbrini M, Storci G, Tomassini E, Dan E, Schipani A, De Matteis S, Sinigaglia B, Messelodi D, Bertuccio NS, Prete A, Brigidi P, Bonifazi F, Masetti R.
Deep learning for automatic segmentation of hepatocellular carcinoma in contrast enhanced CT scans 2025 Spoke 6 Advanced technologies and experimental models Manghi I, Pecchi A, Esposito G, Macheda M, Zanni E, Di Benedetto F, Ferraguti F.
Multifaceted Effects of a Multiple Nitric Oxide Photoreleaser and its Photoproducts on Amyloid-β Aggregation 2026 Spoke 6 Advanced technologies and experimental models Laneri F, Parisi C, Sortino S.
Benefits and concerns of probiotics: an overview of the potential genotoxicity of the colibactin-producing Escherichia coli Nissle 1917 strain 2024 Spoke 5 Advanced technologies and experimental models Falzone L, Lavoro A, Candido S, Salmeri M, Zanghì A, Libra M.
Pistachio leaf waste transformed into a gut-targeted bioactive phytocomplex 2025 Spoke 5 Advanced technologies and experimental models Spampinato M, Furnari S, Siracusa L, Malfa GA, Distefano A, La Spina E, Gulisano M, Furneri PM, Fuochi V, Barbagallo IA.
Discrimination of Tryptophan Enantiomers at Sub-pm Level by Multiparametric Analysis of a Label-Free Organic Immunosensor 2026 Spoke 6 Advanced technologies and experimental models Genitoni M, Greco P, Paradisi A, Sensi M, Berto M, Murgia M, Di Lauro M, Bortolotti CA, Fadiga L, Biscarini F.
The role of polymer coatings in lipid membrane penetration by graphene oxide dots 2025 Spoke 6 Advanced technologies and experimental models Frigerio G, Siani P, Donadoni E, Cui Q, Di Valentin C.
Lactobacilli-Derived Microbe-Associated Molecular Patterns (MAMPs) in Host Immune Modulation 2025 Spoke 5 Advanced technologies and experimental models Furnari S, Ciantia R, Garozzo A, Furneri PM, Fuochi V.
Investigation of Transport in OECTs with Electrochemical Strain Wave Microscopy 2025 Spoke 6 Advanced technologies and experimental models Bonafè F, Ji J, Fabiano S, Fraboni B, Cramer T.
Identification of CD320, SLC44A1 and TNFRSF13B as potential novel therapeutic targets for CAR T-cell therapy in multiple myeloma 2026 Spoke 5 Advanced technologies and experimental models Francesca Garofano , Anna Maria Corsale , Marta Biondo , Andrea Romano , Ingo Schmidt-Wolf , Anna Maria Gullà , Sergio Siragusa , Cirino Botta
Targeting RNA polymerase I to boost natural killer cell anticancer activity in multiple myeloma 2025 Spoke 5 Oncology and innovative therapies Sproviero E, Gnocchini E, Cipollone T, Petillo S, Cassone C, Molfetta R, Zingoni A, Soriani A, Cerboni C, Petrucci MT, Fazio F, Paolini R, Palmieri G, Cippitelli M.
Large scale investigation of GPCR molecular dynamics data uncovers allosteric sites and lateral gateways 2025 Spoke 5 David Aranda-García, David Aranda-García, Tomasz Maciej Stepniewski…ecc.
CFTR Modulator Response in Nasal Organoids Derived from People with Cystic Fibrosis 2025 Spoke 5 Rare diseases and genetic disorders Stefania Lo Cicero , Germana Castelli , Aurora Ceci , Anna Maria Cerio , Giovanna Blaconà ,Mariarita Virgulti , Sara Allushi , Giovanni Sette , Francesca Spadaro , Felice Amato , Paola Melotti , Claudio Sorio , Giuseppe Cimino , Mauro Biffoni , Marco Lucarelli and Adriana Eramo
MAML1 drives Notch and Hedgehog oncogenic pathways by inhibiting Itch activity in triple-negative breast cancer 2026 Spoke 4 Oncology and innovative therapies Sabrina Zema, Francesca Di Fazio, Maria Pelullo, Sara Di Savino, Bruna Cerbelli, Martina Leopizzi, Laura Di Magno, Carmine Nicoletti, Giovanna Peruzzi, Daniel D’Andrea, Maria V Giuli, Samantha Cialfi, Biagio Palmisano, Alice Turdo, Rocco Palermo, Giulia d’Amati, Gianluca Canettieri, Antongiulio Faggiano, Lucia Di Marcotullio, Matilde Todaro, Isabella Screpanti, Claudio Talora, Saula Checquolo, Diana Bellavia
Readthrough Approach Using NV Translational Readthrough-Inducing Drugs (TRIDs): A Study of the Possible Off-Target Effects on Natural Termination Codons (NTCs) on TP53 and Housekeeping Gene Expression 2023 Spoke 5 Advanced technologies and experimental models Perriera, R., Vitale, E., Pibiri, I., Carollo, P. S., Ricci, D., Corrao, F., Fiduccia, I., Melfi, R., Zizzo, M. G., Tutone, M., Pace, A., & Lentini, L.
A precision medicine approach to primary immunodeficiency disease: Ataluren strikes nonsense mutations once again 2025 Spoke 5 Advanced diagnostics Lentini, L., Perriera, R., Corrao, F., Melfi, R., Tutone, M., Carollo, P. S., Fiduccia, I., Pace, A., Ricci, D., Genovese, F., Colige, A., Delvenne, P., Grimbacher, B., Moutschen, M., & Pibiri,I.
SGK1 downregulation co-occurs with leukocyte oligomeric α-synuclein accumulation in Parkinson’s disease 2026 Spoke 4 Neurodegenerative diseases Federica Veltri, Giulia Maria Sancesario, Marco Rosina, Davide Mascioli, Jacopo Bissacco, Matteo Conti, Henri Zenuni, Valentina Nesci, Daniela Maftei, Veronica Buttarazzi, Maria Mancini, Clara Simonetta, Ermanno Berlizzi, Aikaterini Andradi, Federica Todaro, Valerio Chiurchiù, Alberto Ferri, Cristiana Valle, Alessandro Stefani, Nicola Biagio Mercuri, Alfonso Bellia, Davide Lauro, Tommaso Schirinzi
Aligning perspectives: towards a standardized concept of “complexity” in thyroid surgery. An international web-based survey 2025 Spoke 4 Advanced technologies and experimental models Giacomo Di Filippo, Gian Luigi Canu, Leonardo Rossi, Fabio Medas, Federico Cappellacci, Piermarco Papini, Mattia Cammarata, Eleonora Morelli, Giovanni Lazzari, Dorin Serbusca, Alessandro Pasculli, Francesco Paolo Prete, Giuliana Rachele Puglisi, Alessandro Monaco, Luigi Ragucci, Giovanni Cozzolino, Eleonora Lori, Francesco Pennestrì, Pierpaolo Gallucci, Carmela De Crea, Salvatore Sorrenti, Giovanni Docimo, Mario Testini, Marco Raffaelli, Gabriele Materazzi, Pietro Giorgio Calò
CFTR rescue in W1282X cystic fibrosis patient-derived intestinal organoids (PDIOs) mediated by translational readthrough-inducing drugs (TRIDs) 2025 Spoke 5 Rare diseases and genetic disorders Advanced technologies and experimental models Riccardo Perriera, Anabela S Ramalho , Francois Vermeulen , Emanuele Vitale, Ivana Pibiri , Andrea Pace , Laura Lentini
Peptide-mimetics derived from leucyl-tRNA synthetase are potential agents for the therapy of mt-tRNA related diseases 2025 Spoke 4 Advanced technologies and experimental models Pisano A, Belloli S, Pignataro MG, Rainone P, Valtorta S, Coliva A, de Turris V, Mosca L, Di Micco P, Moresco RM, d’Amati G, Morea V.
Photodynamic therapy and nanomedicine: current knowledge, limitations, and applications in oral squamous cell carcinoma: a narrative review 2025 Spoke 4 Spoke 7 Advanced technologies and experimental models Esperouz F, Lorusso M, Santarelli A, De Lillo A, Lo Muzio L, Ciavarella D, Lo Russo L.
Advancing Therapeutic Strategies for Nonsense-Related Diseases: From Small Molecules to Nucleic Acid-Based Innovations 2025 Spoke 5 Ricci, D., Cruciata, I., Fiduccia, I., Vitale, E., Corrao, F., Branchini, A., Carollo, P. S., Pibiri,I., & Lentini, L.
Beyond the stop: Oxadiazole TRIDs restore LRBA protein expression in nonsense-driven primary immunodeficiency 2025 Spoke 5 Ignazio Fiduccia , Emanuele Vitale , Riccardo Varrica , Davide Ricci , Sefora Marino , Antonino Zito , Andrea Pace , Alain Colige , Michel Moutschen , Yasmin Borutzki , Andrea Bileck , Samuel M Meier-Menches , Laura Lentini ,∗, Ivana Pibiri ,∗∗
Congenital granular cell epulis in a neonate: a case report and review of diagnosis, treatment, and prognosis 2025 Spoke 4 Advanced diagnostics Guidone PC, Seccia R, Fabrocini LA, Troiano G, Maffei G, Pedicillo MC, Pannone G, Lo Muzio L, Zamparese R, Mori G, De Stefano IS.
Radiomics-Based Prognostication in Primary Sclerosing Cholangitis: A Proof-of-Concept Study 2025 Spoke 4 Advanced diagnostics Advanced technologies and experimental models Laura Cristoferi , Cesare Maino , Davide Paolo Bernasconi , Ilaria Ripamonti , Miki Scaravaglio , Alberto Savino , Eugenia Pesatori , Alessio Gerussi , Eugenia Nofit , Olga Falco , Daphne D’Amato , Francesca Gallivanone , Chiara Alberzoni , Raffaella Viganò , Chiara Mazzarelli , Luca Saverio Belli , Marco Emilio Dinelli , Massimiliano Mutignani , Maria Grazia Valsecchi , Rocco Corso , Pietro Invernizzi , Marco Carbone , Davide Ippolito , Elisabetta De Bernardi
Benchmarking transcription factor binding site prediction models: a comparative analysis on synthetic and biological data 2025 Spoke 4 Advanced technologies and experimental models Tognon M, Kumbara A, Betti A, Ruggeri L, Giugno R.
Beneath the surface in autoimmune hemolytic anemia: pathogenetic networks, therapeutic advancements and open questions 2025 Spoke 4 Rare diseases and genetic disorders Costa A, Mulas O, Mereu AM, Schintu M, Greco M, Caocci G.
SGSS05-NS3, a covalent SETD8 inhibitor that activates p53 pathway in neuroblastoma 2025 Spoke 4 Preclinical studies on fundamental disease mechanisms Liu, Z., Bagchi, S., Yan, C., Hu, Y., Blum, G., Ma, A., Jin, J., Luo, M., Di Bella, S., Verona, F., Appella, E., Giannini, G., Thiele, C. J., & Veschi, V
Serum HDL-cholesterol is associated with the clinical-biological profile of early-stage Parkinson’s disease patients independently of APOE 2025 Spoke 4 Neurodegenerative diseases Mascioli D, Conti M, Bissacco J, Bovenzi R, Simonetta C, Buttarazzi V, Mancini M, Bagetta S, Sancesario GM, Maftei D, Veltri F, Marchionni E, Stefani A, Mercuri NB, Pieri M, Schirinzi T.
Anodal M1 tDCS shapes frequency-specific functional connectivity and network topology in Parkinson’s disease 2025 Spoke 4 Neurodegenerative diseases Simonetta, C., Conti, M., Bissacco, J., Ferrari, V., Salimei, C., Carparelli, F., Bagetta, S., Mascioli, D., Buttarazzi, V., Mancini, M., Di Giuliano, F., Mercuri, N. B., Pierantozzi, M., Stefani, A., & Schirinzi,T
Automating liver biopsy segmentation with a robust, open-source tool for pathology research: the HOTSPoT model 2025 Spoke 4 Advanced diagnostics Cazzaniga G, L’Imperio V, Bonoldi E, Londoño MC, Madaleno J, Cipriano A, Gevers TJG, Samarska IV, Koc ÖM, Villamil A, Sanchez MF, Calvaruso V, Quattrocchi A, Cabibi D, Engel B, Malinverno F, Merelli E, Cristoferi L, Carbone M, Pagni F, Invernizzi P, Gerussi A.
Nanosensors Made of Halloysite and Kojic Acid Metal Complexes for Dopamine Detection 2025 Spoke 4 Advanced technologies and experimental models Ferlazzo A, Armeli Iapichino MT, Calabrese G, D’Accurso G, Fiorenza R, Pistarà V, Gulino A, Rescifina A, Patamia V, Floresta G
Liver Disease and Periodontal Pathogens: A Bidirectional Relationship Between Liver and Oral Microbiota 2025 Spoke 4 Preclinical studies on fundamental disease mechanisms Dioguardi M, Lo Muzio E, Guerra C, Sovereto D, Laneve E, Martella A, Aiuto R, Garcovich D, Caloro GA, Cantore S, Lo Muzio L, Ballini A.
Predictors of Suboptimal Response After Radiofrequency Ablation of Benign Thyroid Nodules 2025 Spoke 4 Advanced diagnostics Oncology and innovative therapies Di Filippo G, Medas F, Gobbo G, Rossi L, Lazzari G, Serbusca D, Morelli E, Cappellacci F, Puccini M, Materazzi G, Canu GL.
Artificial Intelligence in Meta-Analysis: A Potential Tool for Improving Data Accuracy and Interpretation 2025 Spoke 4 Advanced diagnostics Calzetta, L., & Rogliani, P.
DiGAS: Differential gene allele spectrum as a descriptor in genetic studies 2024 Spoke 4 Rare diseases and genetic disorders Preclinical studies on fundamental disease mechanisms Aparo, A., Bonnici, V., Avesani, S., Cascione, L., Giugno, R., & Alzheimer’s Disease Neuroimaging Initiative.
CSF phospho-tau levels at Parkinson’s disease onset predict the risk for development of motor complications 2025 Spoke 4 Neurodegenerative diseases Bissacco J, Di Lazzaro G, Bovenzi R, Sancesario GM, Conti M, Simonetta C, Mascioli D, Mancini M, Buttarazzi V, Pierantozzi M, Pieri M, Bernardini S, Stefani A, Bentivoglio AR, Calabresi P, Mercuri NB, Schirinzi T.
Diagnostic Yield of Whole Exome Sequencing in Adult-onset Cholestatic Liver Disease 2026 Spoke 4 Rare diseases and genetic disorders Scaravaglio M, Ronzoni L, Cristoferi L, Miano L, Nofit E, Gerussi A, Malinverno F, Moretti V, Torcianti V, Caime C, Cadamuro M, D’Antiga L, Invernizzi P, Carbone M, Valenti L.
EasyCircR: Detection and reconstruction of circular RNAs post-transcriptional regulatory interaction networks 2025 Spoke 4 Advanced diagnostics Advanced technologies and experimental models Aparo, A., Avesani, S., Parmigiani, L., Napoli, S., Bertoni, F., Bonnici, V., Cascione, L., & Giugno, R.
Novel Pathogenic Variant Confirms the Association of REST and Jones Syndrome 2026 Spoke 4 Rare diseases and genetic disorders Lodato V, Galli M, D’Angeli G, Bottillo I, Celli L, Turchetta R, Colizza A, Gianno F, Palmisano B, Stanganelli FRF, Bianco MR, Messineo D, Allegra E, Grammatico P, Riminucci M, Corsi A.
